DNA sequence of the transfer RNA region of bacteriophage T4: implications for transfer RNA synthesis. | Zendy

Gail P. Mazzara | Zendy; Guy Plunkett | Zendy; William H. McClain | Zendy

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DNA sequence of the transfer RNA region of bacteriophage T4: implications for transfer RNA synthesis.

Author(s) -

Gail P. Mazzara,

Guy Plunkett,

William H. McClain

Publication year - 1981

Publication title -

proceedings of the national academy of sciences

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.011

H-Index - 771

eISSN - 1091-6490

pISSN - 0027-8424

DOI - 10.1073/pnas.78.2.889

Subject(s) - rna , dna , bacteriophage , biology , sequence (biology) , base pair , genetics , transfer rna , genome , nucleic acid , computational biology , gene , escherichia coli

Sequences encoding eight tRNAs and two stable RNAs of bacteriophage T4 are grouped together on the T4 genome in two clusters, separated by approximately 500 base pairs. The DNA sequence of part of this region was determined. Within each cluster coding sequences are separated by only one or a few base pairs. These findings imply that the RNAs may be processed from a single multimeric transcript, with initial endonucleolytic cleavages generating the previously characterized monomeric and dimeric precursors.

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