Engrailed: a gene controlling compartment and segment formation in Drosophila. | Zendy

Thomas B. Kornberg | Zendy

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Engrailed: a gene controlling compartment and segment formation in Drosophila.

Author(s) -

Thomas B. Kornberg

Publication year - 1981

Publication title -

proceedings of the national academy of sciences

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.011

H-Index - 771

eISSN - 1091-6490

pISSN - 0027-8424

DOI - 10.1073/pnas.78.2.1095

Subject(s) - engrailed , locus (genetics) , biology , compartment (ship) , gene , genetics , drosophilidae , microbiology and biotechnology , drosophila melanogaster , gene expression , homeobox , oceanography , geology

A total of 58 mutations at the engrailed locus were isolated. Analysis suggests that this genetic locus is necessary for survival but required only in the cells of the posterior compartments. Inactivation of the engrailed locus renders the animal incapable of maintaining the separation between the groups of cells that constitute either the compartments that subdivide each segment or the individual segments themselves.

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