Open AccessA suggestion for naming faces of ring compounds
Author(s) -
Irwin A. Rose,
Kenneth R. Hanson,
Keith D. Wilkinson,
Mary J. Wimmer
Publication year - 1980
Publication title -
proceedings of the national academy of sciences
Language(s) - English
Resource type - Journals
eISSN - 1091-6490
pISSN - 0027-8424
DOI - 10.1073/pnas.77.5.2439
Subject(s) - ring (chemistry) , stereochemistry , numbering , chemistry , macromolecule , crystallography , topology (electrical circuits) , computer science , combinatorics , mathematics , organic chemistry , biochemistry , programming language
Discussion of the topology of interaction of ring compounds with macromolecules and receptors requires a system for naming the faces of the cyclic compound. An α/β-face nomenclature is suggested that is based on the clockwise/counterclockwise direction of ascending numbering in the ring with the lowest numbered unshared ring atom. This system is applicable to a very broad range of compounds: sugars, cyclic bases, steroids, cyclitols, porphyrins, etc., and molecules with a single ring, fused rings, encompassing rings, and rings formed by head-to-tail polymerization.
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