Open AccessA human protein related to the major envelope protein of murine mammary tumor virus: identification and characterization.
Author(s) -
Arnold S. Dion,
Donald C. Farwell,
Anthony A. Pomenti,
Anthony J. Girardi
Publication year - 1980
Publication title -
proceedings of the national academy of sciences of the united states of america
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.011
H-Index - 771
eISSN - 1091-6490
pISSN - 0027-8424
DOI - 10.1073/pnas.77.3.1301
Subject(s) - mouse mammary tumor virus , glycoprotein , biology , virus , homologous chromosome , viral envelope , virology , microbiology and biotechnology , genetics , gene
A human milk protein was isolated to apparent homogeneity and shown to be immunologically related to gp55, the major envelope glycoprotein of murine mammary tumor virus. Through the development of ultrasensitive protocols, which have wide applicability, immunological relatedness was corroborated by the demonstration of homologous protein sequences between the human and viral proteins.