The rat serum albumin gene: analysis of cloned sequences.
Author(s) -
Thomas D. Sargent,
J R Wu,
J M Sala-Trepat,
R. Bruce Wallace,
Antonio A. Reyes,
James C. Bonner
Publication year - 1979
Publication title -
proceedings of the national academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.011
H-Index - 771
eISSN - 1091-6490
pISSN - 0027-8424
DOI - 10.1073/pnas.76.7.3256
Subject(s) - intron , exon , microbiology and biotechnology , gene , biology , genomic dna , recombinant dna , genome , genomic library , genetics , dna , peptide sequence
The rat serum albumin gene has been isolated from a recombinant library containing the entire rat genome cloned in the lambda phage Charon 4A. Preliminary R-loop and restriction analysis has revealed that this gene is split into at least 14 fragments (exons) by 13 intervening sequences (introns), and that it occupies a minimum of 14.5 kilobases of genomic DNA.
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