Arrangement of coding and intervening sequences of chicken lysozyme gene. | Zendy

Werner Lindenmaier | Zendy; M. Chi Nguyen-Huu | Zendy; R. Lurz | Zendy; Markus Stratmann | Zendy; Nikolaus Blin | Zendy; Tilmann Wurtz | Zendy; Howard Hauser | Zendy; Albrecht E. Sippel | Zendy; G. Schütz | Zendy

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Arrangement of coding and intervening sequences of chicken lysozyme gene.

Author(s) -

Werner Lindenmaier,

M. Chi Nguyen-Huu,

R. Lurz,

Markus Stratmann,

Nikolaus Blin,

Tilmann Wurtz,

Howard Hauser,

Albrecht E. Sippel,

G. Schütz

Publication year - 1979

Publication title -

proceedings of the national academy of sciences

Language(s) - English

Resource type - Journals

eISSN - 1091-6490

pISSN - 0027-8424

DOI - 10.1073/pnas.76.12.6196

Subject(s) - lysozyme , gene , biology , microbiology and biotechnology , dna , restriction map , genetics , coding region , restriction enzyme , nucleic acid thermodynamics , gene expression , nucleic acid sequence , rna

Hybrid phages that contain chicken lysozyme gene sequences have been isolated from a chicken DNA library. Two overlapping clones covering a region of 22 kilobase pairs around this gene have been studied by restriction mapping. Southern hybridization, and electron microscopic analysis of hybrids between lysozyme mRNA and the cloned cellular DNA. Three intervening sequences interrupt the lysozyme structural gene. The cellular gene is at least 3.9 kilobases long, about 6 times the length of the structural gene.

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