Cooperativity in O2 binding to iron porphyrins. | Zendy

James P. Collman | Zendy; John I. Brauman | Zendy; Éric Rose | Zendy; Kenneth S. Suslick | Zendy

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Cooperativity in O2 binding to iron porphyrins.

Author(s) -

James P. Collman,

John I. Brauman,

Éric Rose,

Kenneth S. Suslick

Publication year - 1978

Publication title -

proceedings of the national academy of sciences

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.011

H-Index - 771

eISSN - 1091-6490

pISSN - 0027-8424

DOI - 10.1073/pnas.75.3.1052

Subject(s) - cooperativity , chemistry , ferrous , steric effects , cooperative binding , diphosphoglycerate , hemoglobin , crystallography , binding site , stereochemistry , biochemistry , organic chemistry

The solid-gas O2 binding equilibrium has been studied for for ferrous "picket fence" porphyrinates with sterically hindered axial imidazoles. Such systems show significant cooperativity in their binding of O2: at low O2 pressures a low O2 affinity form exists, and at high O2 pressures a higher O2 affinity form develops. Direct analogies are drawn to the cooperativity shown in O2 binding by hemoglobin. These model systems mimic hemoglobin quantitatively.

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