Open AccessGenetic instability in Drosophila melanogaster: De novo induction of putative insertion mutations
Author(s) -
M. M. Green
Publication year - 1977
Publication title -
proceedings of the national academy of sciences of the united states of america
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.011
H-Index - 771
eISSN - 1091-6490
pISSN - 0027-8424
DOI - 10.1073/pnas.74.8.3490
Subject(s) - genetics , drosophila melanogaster , biology , locus (genetics) , mutant , insertion , phenotype , mutation , chromosome , recombination , microbiology and biotechnology , gene
The capacity of a so-called male recombination (MR) chromosome inDrosophila melanogaster to generate mutations at 14 X-chromosome loci specifying visible phenotypes was investigated. Appreciable increases in mutation were found at three lociy, sn , andras . Tests of represnetative mutants generated at each locus establish all to be putative insertion mutants, as judged by their spontaneous mutability. These facts suggest that insertion mutation production may be a general function of MR chromosomes. The relationship of the MR chromosomes to established insertion elements (IS and Mu) is discussed.