Suppression of production of mouse 28S ribosomal RNA in mouse-human hybrids segregating mouse chromosomes. | Zendy

C M Croce | Zendy; Antonio Talavera | Zendy; Claudio Basilico | Zendy; O. J. Miller | Zendy

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Suppression of production of mouse 28S ribosomal RNA in mouse-human hybrids segregating mouse chromosomes.

Author(s) -

C M Croce,

Antonio Talavera,

Claudio Basilico,

O. J. Miller

Publication year - 1977

Publication title -

proceedings of the national academy of sciences

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.011

H-Index - 771

eISSN - 1091-6490

pISSN - 0027-8424

DOI - 10.1073/pnas.74.2.694

Subject(s) - 28s ribosomal rna , ribosomal rna , biology , rna , microbiology and biotechnology , genetics , gene , 5s ribosomal rna , somatic cell , ribosome , 18s ribosomal rna

Mouse-human somatic cell hybrids that lose (segregate) human chromosomes produce only mouse 28S ribosomal RNA even when they retain copies of the human chromosomes that contain the genes for 28S ribosomal RNA. In contrast, mouse-human hybrid cells that segregate mouse chromosomes produce only human 28S ribosomal RNA even when they have retained copies of mouse chromosomes that contain the 28S ribosomal RNA genes.

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