Cells reconstituted from cell fragments of two different species multiply and form colonies. | Zendy

Ulla Krondahl | Zendy; Niels C. Bols | Zendy; T. Ege | Zendy; Stig Linder | Zendy; Nils R. Ringertz | Zendy

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Cells reconstituted from cell fragments of two different species multiply and form colonies.

Author(s) -

Ulla Krondahl,

Niels C. Bols,

T. Ege,

Stig Linder,

Nils R. Ringertz

Publication year - 1977

Publication title -

proceedings of the national academy of sciences

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.011

H-Index - 771

eISSN - 1091-6490

pISSN - 0027-8424

DOI - 10.1073/pnas.74.2.606

Subject(s) - sendai virus , cell fusion , cell , virus , enucleation , microbiology and biotechnology , cytoplasm , cytochalasin b , biology , fibroblast , cytochalasin , cell culture , chemistry , virology , biochemistry , genetics , cytoskeleton

Nuclei (minicells) prepared by cytochalasin-induced enucleation of rat myoblasts (L6) were fused with inactivated Sendai virus to preparations of cytoplasms from mouse fibroblasts (A9). Cell colonies arising from such fusion mixtures were examined 5 days after fusion. In the presence of virus a new type of colony was obtained. The cells in these colonies were derived from reconstituted cells capable of undergoing repeated cell divisions.

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