Open AccessDNA sequence organization in the water mold Achlya
Author(s) -
Michael E. S. Hudspeth,
William E. Timberlake,
Robert B. Goldberg
Publication year - 1977
Publication title -
proceedings of the national academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.011
H-Index - 771
eISSN - 1091-6490
pISSN - 0027-8424
DOI - 10.1073/pnas.74.10.4332
Subject(s) - eukaryote , biology , dna , dna sequencing , gene , genome , genetics , slime mold , repeated sequence , sequence (biology) , genomic organization , computational biology , botany
Experiments are described that characterize the organization of DNA sequences in the water moldAchlya bisexualis . These experiments demonstrate that repetitive and single copy sequences in theAchlya genome are arranged in a long-period interspersion pattern. Estimates of the spacing intervals between repetitive and single copy DNA indicate, however, that the interspersion pattern inAchlya is longer than has been previously reported in other eukaryotes. These data and measurements of structural gene expression inAchlya [Timberlake, W.E., Shumard, D. S. & Goldberg, R. B. (1977)Cell 10, 623-632] make it difficult to propose a regulatory function for repeated DNA in this eukaryote.
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