Antigen-specific nonimmunoglobulin factor that neutralizes xenotropic virus is associated with mouse serum lipoproteins. | Zendy

JoAnn C. Leong | Zendy; John P. Kane | Zendy; O Oleszko | Zendy; Jay A. Levy | Zendy

Open Access

Antigen-specific nonimmunoglobulin factor that neutralizes xenotropic virus is associated with mouse serum lipoproteins.

Author(s) -

JoAnn C. Leong,

John P. Kane,

O Oleszko,

Jay A. Levy

Publication year - 1977

Publication title -

proceedings of the national academy of sciences

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.011

H-Index - 771

eISSN - 1091-6490

pISSN - 0027-8424

DOI - 10.1073/pnas.74.1.276

Subject(s) - ultracentrifuge , antibody , chemistry , antigen , virus , virology , microbiology and biotechnology , biology , biochemistry , immunology

A soluble nonimmunoglobulin factor that specifically neutralizes mouse xenotropic C-type virus is found in normal mouse sera. It is stable from pH 2 to neutrality and resists ether extraction, freezing, or brief heating to 100 degrees. It can be separated from immunoglobulins by ultracentrifugation at a density of 1.21 g/cm3. Neutralizing activity is only found with the serum lipoproteins in the fraction with density less than 1.21 g/cm3.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research