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Immunoreactive somatostatin is present in discrete cells of the endocrine pancreas.
Author(s) -
M.P. Dubois
Publication year - 1975
Publication title -
proceedings of the national academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.011
H-Index - 771
eISSN - 1091-6490
pISSN - 0027-8424
DOI - 10.1073/pnas.72.4.1340
Subject(s) - somatostatin , glucagon , pancreas , endocrine system , enteroendocrine cell , endocrinology , medicine , population , insulin , somatostatin receptor 3 , immunofluorescence , biology , hormone , somatostatin receptor 2 , antibody , somatostatin receptor , immunology , environmental health
A discrete population of cells of the endocrine pancreas contains immunoreactive somatostatin as shown by immunofluorescence. These cells are different from those containing glucagon or insulin. This unexpected observation may be of physiopathological significance in the regulatory mechanisms involved in the secretion of glucagon and insulin.

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