The Role of Cytoplasmic Membranes in Controlling the Transport of Nuclear Messenger RNA and Initiation of Protein Synthesis | Zendy

K. Shiokawa | Zendy; A.O. Pogo | Zendy

Open Access

The Role of Cytoplasmic Membranes in Controlling the Transport of Nuclear Messenger RNA and Initiation of Protein Synthesis

Author(s) -

K. Shiokawa,

A.O. Pogo

Publication year - 1974

Publication title -

proceedings of the national academy of sciences

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.011

H-Index - 771

eISSN - 1091-6490

pISSN - 0027-8424

DOI - 10.1073/pnas.71.7.2658

Subject(s) - rna , messenger rna , cytoplasm , five prime cap , protein biosynthesis , biochemistry , chemistry , microbiology and biotechnology , biology , non coding rna , gene

Three different classes of poly(A)-containing RNA have been identified in the yeast system. They have been characterized by their kinetics of labeling, by their localization in the nuclear, membranous, and soluble cytoplasmic fractions, and by their size. The evidence indicates that the membrane-bound poly(A)-containing RNA is a product of the nuclear poly(A)-containing RNA and is the precursor of the polysomal poly(A)-containing RNA. In addition, it has been demonstrated that transport of mRNA is coupled with protein synthesis.

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