Open AccessCyclic 3′:5′-Adenosine Monosphate in Escherichia coli during Transient and Catabolite Repression
Author(s) -
Peter K. Wayne,
Ora M. Rosen
Publication year - 1974
Publication title -
proceedings of the national academy of sciences of the united states of america
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.011
H-Index - 771
eISSN - 1091-6490
pISSN - 0027-8424
DOI - 10.1073/pnas.71.4.1436
Subject(s) - catabolite repression , escherichia coli , fed batch culture , psychological repression , adenosine , chemistry , transient (computer programming) , biochemistry , computer science , gene , fermentation , mutant , operating system , gene expression
Cyclic AMP concentrations were low for an adenylate cyclase-deficient mutant (cya - ) and abnormally high for a catabolite receptor protein-deficient mutant (crp - ). A fall in cellular cAMP concentration was always found when cells were subjected to transient repression. No consistent correlations were observed between catabolite repression and cellular cAMP levels.