Open AccessVisual Detection of Hepatitis B Antigen
Author(s) -
Ivar Giæver,
Robert J. Laffin
Publication year - 1974
Publication title -
proceedings of the national academy of sciences of the united states of america
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.011
H-Index - 771
eISSN - 1091-6490
pISSN - 0027-8424
DOI - 10.1073/pnas.71.11.4533
Subject(s) - radioimmunoassay , antigen , antibody , hepatitis b , chemistry , virology , microbiology and biotechnology , immunology , medicine , biology , biochemistry
When the hepatitis B antigen is first adsorbed on a specially prepared metal surface, the subsequent reaction with its specific antibody produces complexes that are visible to the unaided eye. Application of this principle has led to the development of tests for both antigen and antibody that compare favorably with the sensitivity obtained by radioimmunoassay.