Open AccessEnhancement of Tumor Growth by Graft-versus-host Reaction
Author(s) -
Shinji Okubo,
Herbert F. Oettgen,
Stephen S. Caiazza,
Zoltán Óváry
Publication year - 1974
Publication title -
proceedings of the national academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.011
H-Index - 771
eISSN - 1091-6490
pISSN - 0027-8424
DOI - 10.1073/pnas.71.10.4264
Subject(s) - host (biology) , graft vs host reaction , chemistry , biology , medicine , transplantation , genetics , bone marrow transplantation
A graft-versus-host reaction was induced in (BALB/c x C5 7BL/6)F(1) mice by intravenous injection of BALB/c spleen cells. Six days later, the mice received subcutaneous grafts of a chemically induced BALB/c sarcoma. The growth of the tumor grafts was accelerated.
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