Open AccessThe Kinetics of Hemolytic Plaque Formation
Author(s) -
Charles P. De Lisi,
George I. Bell
Publication year - 1974
Publication title -
proceedings of the national academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.011
H-Index - 771
eISSN - 1091-6490
pISSN - 0027-8424
DOI - 10.1073/pnas.71.1.16
Subject(s) - antibody , kinetics , antigen , agar , chemistry , microbiology and biotechnology , biology , immunology , bacteria , genetics , physics , quantum mechanics
A mathematical analysis of the formation of hemolytic plaques in agar is presented. The results can be used to calculate the rate constant for antigen-antibody association and the distribution of antibody secretion rates. The limitations of the treatment and estimates of the expected errors involved are briefly discussed.
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