Discrimination between Messenger Ribonucleic Acids by a Mammalian Translation Initiation Factor | Zendy

Uri Nudel | Zendy; Bernard Lebleu | Zendy; Michel Revel | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Discrimination between Messenger Ribonucleic Acids by a Mammalian Translation Initiation Factor

Author(s) -

Uri Nudel,

Bernard Lebleu,

Michel Revel

Publication year - 1973

Publication title -

proceedings of the national academy of sciences

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.011

H-Index - 771

eISSN - 1091-6490

pISSN - 0027-8424

DOI - 10.1073/pnas.70.7.2139

Subject(s) - reticulocyte , messenger rna , translation (biology) , protein biosynthesis , initiation factor , biology , rna , globin , microbiology and biotechnology , biochemistry , ribosome , chemistry , hemoglobin , gene

A factor from rabbit-reticulocyte ribosome, which stimulates by 5-fold initiation of hemoglobin mRNA translation in Krebs ascites cell extracts, was purified to homogeneity. The factor, a protein of about 65,000 molecular weight in sodium dodecyl sulfate, discriminates between various mRNAs: it stimulates translation of alpha globin mRNA and of tobacco mosaic virus RNA, but has only a small effect on beta globin mRNA and no effect at all on Mengo virus RNA translation.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research