Fusion of Phospholipid Vesicles with Viable Acholeplasma laidlawii | Zendy

Chris W.M. Grant | Zendy; Harden M. McConnell | Zendy

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Fusion of Phospholipid Vesicles with Viable Acholeplasma laidlawii

Author(s) -

Chris W.M. Grant,

Harden M. McConnell

Publication year - 1973

Publication title -

proceedings of the national academy of sciences

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.011

H-Index - 771

eISSN - 1091-6490

pISSN - 0027-8424

DOI - 10.1073/pnas.70.4.1238

Subject(s) - vesicle , phosphatidylcholine , phospholipid , sonication , lipid bilayer fusion , chemistry , membrane , cytoplasm , liposome , mycoplasma , biochemistry , biology , biophysics , chromatography , microbiology and biotechnology

When vesicles of dipalmitoyl phosphatidylcholine produced by sonication are mixed with Acholeplasma laidlawii in neutral buffer, a phenomenon occurs that is most readily explained in terms of fusion of lipid vesicle membrane with the mycoplasma cytoplasmic membrane. The mycoplasma can readily accumulate large quantities of the foreign lipid without loss of viability. The added lipids do not remain in patches but diffuse laterally throughout the mycoplasma membrane.

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