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Adenosine 3′:5′-Cyclic Monophosphate as a Regulator of Bacterial Transformation
Author(s) -
Edmund M. Wise,
Susan P. Alexander,
Marilyn Powers
Publication year - 1973
Publication title -
proceedings of the national academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.011
H-Index - 771
eISSN - 1091-6490
pISSN - 0027-8424
DOI - 10.1073/pnas.70.2.471
Subject(s) - stationary phase , adenosine , regulator , competence (human resources) , chemistry , microbiology and biotechnology , biochemistry , biophysics , biology , gene , chromatography , psychology , social psychology
Adenosine 3′:5′-cyclic monophosphate added to exponentially growing cells ofHemophilus influenzae strain Rd increases competence for transformation 100- to 10,000-fold. Cyclic AMP added to near-stationary or stationary cells does not increase competence over the high level normally found in the early stationary phase.

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