Open AccessRelatedness of Mouse Satellite Deoxyribonucleic Acid to Deoxyribonucleic Acid of Various Mus Species
Author(s) -
Nancy R. Rice,
Neil A. Straus
Publication year - 1973
Publication title -
proceedings of the national academy of sciences of the united states of america
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.011
H-Index - 771
eISSN - 1091-6490
pISSN - 0027-8424
DOI - 10.1073/pnas.70.12.3546
Subject(s) - satellite dna , biology , dna , subspecies , homologous chromosome , satellite , microbiology and biotechnology , nucleic acid thermodynamics , genetics , gene , genome , base sequence , zoology , engineering , aerospace engineering
Mouse (Mus musculus musculus ) satellite DNA is able to reassociate with repeated DNA sequences ofMus caroli andMus cervicolor , but low thermal stability of the products indicates significant differences between satellite and related DNAs of these twoMus species. There appear to be several satellite-related populations inM .caroli DNA, each of which forms hybrids of low thermal stability with repeated sequences ofM .cervicolor DNA. DNAs from the subspeciesMus musculus molossinus andMus musculus castaneus reassociate with mouse satellite to form hybrids of very high thermal stability, but the satellite content ofM .m .musculus DNA is only about 60% that ofM .m .musculus DNA. Reassociation ofM .m .musculus nonrepeated DNA withM. m. molossinus DNA reveals no detectable differences between them; reassociation withM. caroli (orM. cervicolor ) DNA yields a product whose melting temperature depression relative to homologous DNA is about 5°.