Prebiotic Synthesis of Hydrophobic and Protein Amino Acids | Zendy

David Ring | Zendy; Y. Wolman | Zendy; Nadav Friedmann | Zendy; Stanley L. Miller | Zendy

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Prebiotic Synthesis of Hydrophobic and Protein Amino Acids

Author(s) -

David Ring,

Y. Wolman,

Nadav Friedmann,

Stanley L. Miller

Publication year - 1972

Publication title -

proceedings of the national academy of sciences

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.011

H-Index - 771

eISSN - 1091-6490

pISSN - 0027-8424

DOI - 10.1073/pnas.69.3.765

Subject(s) - norleucine , amino acid , norvaline , chemistry , valine , alanine , leucine , isoleucine , amino acid synthesis , glycine , aspartic acid , organic chemistry , chromatography , biochemistry , lysine

The formation of amino acids by the action of electric discharges on a mixture of methane, nitrogen, and water with traces of ammonia was studied in detail. The presence of glycine, alanine, alpha-amino-n-butyric acid, alpha-aminoisobutyric acid, valine, norvaline, isovaline, leucine, isoleucine, alloisoleucine, norleucine, proline, aspartic acid, glutamic acid, serine, threonine, allothreonine, alpha-hydroxy-gamma-aminobutyric acid, and alpha,gamma-diaminobutyric acid was confirmed by ion-exchange chromatography and gas chromatography-mass spectrometry. All of the primary alpha-amino acids found in the Murchison Meteorite have been synthesized by this electric discharge experiment.

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