Human Placental 15-Hydroxyprostaglandin Dehydrogenase | Zendy

Joseph Jarabak | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Human Placental 15-Hydroxyprostaglandin Dehydrogenase

Author(s) -

Joseph Jarabak

Publication year - 1972

Publication title -

proceedings of the national academy of sciences

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.011

H-Index - 771

eISSN - 1091-6490

pISSN - 0027-8424

DOI - 10.1073/pnas.69.3.533

Subject(s) - dehydrogenase , enzyme , nad+ kinase , chemistry , biochemistry , glycerol , human placenta , placenta , biology , fetus , pregnancy , genetics

Normal, term, human placentas are a rich source of a 15-hydroxyprostaglandin dehydrogenase. The enzyme is extremely labile, and partial purification could be achieved only after stabilization with glycerol. The instability of the enzyme and itsK m for NAD are indications that it is different from the 15-hydroxyprostaglandin dehydrogenase isolated from swine lung. Human placental tissue should provide a very useful source from which large amounts of highly purified 15-hydroxyprostaglandin dehydrogenase may be obtained.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research