Open AccessDNA-Dependent DNA Polymerases I and II from Normal Human-Blood Lymphocytes
Author(s) -
R. Graham Smith,
Robert C. Gallo
Publication year - 1972
Publication title -
proceedings of the national academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.011
H-Index - 771
eISSN - 1091-6490
pISSN - 0027-8424
DOI - 10.1073/pnas.69.10.2879
Subject(s) - dna polymerase , polymerase , biology , microbiology and biotechnology , dna polymerase ii , dna , dna polymerase mu , primase , primer (cosmetics) , dna clamp , genetics , rna , chemistry , reverse transcriptase , circular bacterial chromosome , gene , organic chemistry
Two DNA polymerases have been purified from blood lymphocytes of normal human individuals. In contrast to a DNA polymerase isolated from lymphoblasts from individuals with leukemia, neither of the DNA polymerases from normal lymphocytes transcribes the heteropolymeric regions of tumor-virus RNA into DNA.
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