Specific Banding Patterns of Human Chromosomes | Zendy

Máximo E. Drets | Zendy; Margery W. Shaw | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Specific Banding Patterns of Human Chromosomes

Author(s) -

Máximo E. Drets,

Margery W. Shaw

Publication year - 1971

Publication title -

proceedings of the national academy of sciences

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.011

H-Index - 771

eISSN - 1091-6490

pISSN - 0027-8424

DOI - 10.1073/pnas.68.9.2073

Subject(s) - trisodium citrate , giemsa stain , g banding , chromosome , biology , genetics , staining , karyotype , microbiology and biotechnology , biochemistry , gene

Individual pairs of human chromosomes can be reliably identified by a new method that does not require special optical equipment and that results in permanent preparations. This method, which is based on treatment of the chromosomesin situ with NaOH, followed by incubation in sodium chloride-trisodium citrate and Giemsa staining, results in highly specific banding patterns in characteristic regions of the chromosome arms. It should prove useful for the detection of small structural changes in chromosomes.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research