Nature and Self-Regulated Synthesis of the Repressor of the hut Operons in Salmonella typhimurium | Zendy

Gerald R. Smith | Zendy; Boris Magasanik | Zendy

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Nature and Self-Regulated Synthesis of the Repressor of the hut Operons in Salmonella typhimurium

Author(s) -

Gerald R. Smith,

Boris Magasanik

Publication year - 1971

Publication title -

proceedings of the national academy of sciences

Language(s) - English

Resource type - Journals

eISSN - 1091-6490

pISSN - 0027-8424

DOI - 10.1073/pnas.68.7.1493

Subject(s) - operon , repressor , gene , salmonella , l arabinose operon , biology , lac operon , trp operon , genetics , escherichia coli , bacteria , gene expression

The enzymes mediating histidine utilization, coded by thehut genes, inSalmonella typhimurium are synthesized from two closely-linked operons. Results presented in this paper show that these operons are regulated by a single repressor protein. ThehutC gene, coding for this repressor, is part of one of the operons. Since this same operon is sensitive to the repressor, the repressor apparently represses its own synthesis.

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