Allotypy of High Density Lipoprotein of Rabbit Serum
Author(s) -
Kåre Berg,
Helge Boman,
Harald Torsvik,
Suzanne M. Walker
Publication year - 1971
Publication title -
proceedings of the national academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.011
H-Index - 771
eISSN - 1091-6490
pISSN - 0027-8424
DOI - 10.1073/pnas.68.5.905
Subject(s) - high density lipoprotein , biology , lipoprotein , polymorphism (computer science) , genetics , antigen , cholesterol , allele , endocrinology , gene
A common antigenic polymorphism of high density lipoprotein (HDL) in rabbit serum is described. The presence or absence of an antigen termed Hl 1 appears to be controlled by autosomal dominant inheritance. The polymorphism should be a useful tool in the study of serum lipoproteins, particularly since genetic polymorphisms within the low density lipoprotein are already known in several species. The Hl polymorphism may make the rabbit more useful for model studies of serum lipoproteins in health and disease.
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