Open AccessPurification of Erythropoietin
Author(s) -
Eugene Goldwasser,
Charles Kung
Publication year - 1971
Publication title -
proceedings of the national academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.011
H-Index - 771
eISSN - 1091-6490
pISSN - 0027-8424
DOI - 10.1073/pnas.68.4.697
Subject(s) - erythropoietin , regulator , polyacrylamide gel electrophoresis , chemistry , hormone , biology , chromatography , biochemistry , endocrinology , enzyme , gene
Erythropoietin, the hormone that is the primary regulator of erythrocyte production, has been purified from anemic-sheep plasma, with a purification factor of more than 1 million. Gel electrophoresis shows that the major contaminant is desialated erythropoietin.
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