Open AccessStructure of the Replicating DNA from Bacteriophage T4
Author(s) -
Hajo Delius,
Chin C. Howe,
Andrzej W. Kozinski
Publication year - 1971
Publication title -
proceedings of the national academy of sciences of the united states of america
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.011
H-Index - 771
eISSN - 1091-6490
pISSN - 0027-8424
DOI - 10.1073/pnas.68.12.3049
Subject(s) - bacteriophage , dna , dna replication , loop (graph theory) , biology , whiskers , genetics , biophysics , paleontology , mathematics , gene , escherichia coli , combinatorics
At an early stage of replication, parental T4 DNA shows a loop structure often displaying two 3′-ended, single-stranded “whiskers”, located intrans configuration at the branching-points. Several such loops have been observed within a single T4 molecule. Occasionally, reinitiation occurred in the middle of a loop, which suggests that the loop was growing in both directions.