Open AccessAn Adenosine 3′:5′-Cyclic Monophosphate-Binding Protein That Acts on the Transcription Process
Author(s) -
L J Eron,
R. Rita Arditti,
Geoffrey Zubay,
S. Connaway,
J Beckwith
Publication year - 1971
Publication title -
proceedings of the national academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.011
H-Index - 771
eISSN - 1091-6490
pISSN - 0027-8424
DOI - 10.1073/pnas.68.1.215
Subject(s) - transcription (linguistics) , lac operon , operon , transcription factor , in vitro , microbiology and biotechnology , chemistry , taf2 , biology , biochemistry , gene expression , gene , escherichia coli , enhancer , philosophy , linguistics
An assay system for the in vitro transcription of the lac operon is described. A protein factor (CAP) and cyclic AMP, which are essential for the lac expression in vivo, also stimulate lac transcription in vitro.
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