Open AccessReplication of Repetitious DNA and the S Period
Author(s) -
David E. Comings,
Emilio Mattoccia
Publication year - 1970
Publication title -
proceedings of the national academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.011
H-Index - 771
eISSN - 1091-6490
pISSN - 0027-8424
DOI - 10.1073/pnas.67.1.448
Subject(s) - dna replication , dna , replicon , biology , satellite dna , euchromatin , period (music) , genetics , microbiology and biotechnology , eukaryotic dna replication , control of chromosome duplication , chromosome , chromatin , gene , plasmid , heterochromatin , physics , acoustics
The renaturation kinetics of labeled DNA derived from synchronized Chinese hamster cells indicate that the three classes of repetitious DNA replicate uniformly throughout the S period, and that a piece of repetitious DNA may occur at or near the beginning of each replicon. Studies with mouse-cell DNA suggest that mouse satellite DNA replicates when euchromatin replicates.
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