Open AccessStability of a Position-Effect Variegation in Normal and Transdetermined Larval Blastemas from Drosophila melanogaster
Author(s) -
Ernst Hadorn,
Robert Gsell,
Jack C. Schultz
Publication year - 1970
Publication title -
proceedings of the national academy of sciences of the united states of america
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.011
H-Index - 771
eISSN - 1091-6490
pISSN - 0027-8424
DOI - 10.1073/pnas.65.3.633
Subject(s) - variegation (histology) , blastema , biology , drosophila melanogaster , larva , genetics , microbiology and biotechnology , anatomy , botany , regeneration (biology) , gene
Male genital disks of a yellow-variegated genotype were implanted into the abdomens of adult females to test the stability of variegated clones in the blastemas formed by the implants. Upon reimplantation into metamorphosing larval hosts, test fragments of the proliferating blastemas differentiated into variegated organs, withyellow and wild-type areas. In later transfer generations clones were separated, which appeared stable for either wild type oryellow; variegation was no longer occurring. In all the lines differentiation occurred also into other organs (allotypic) than those characteristically formed by the genital disc (transdetermination). The absence of new variegation in these transdetermined organs is discussed as evidence against a reversal to the embryonic state in the cells of the transdetermining blastema. The variegation process seems not to be affected by, nor does it in this case influence, the process of transdetermination.