Open AccessAN ATP-DEPENDENT DEOXYRIBONUCLEASE FROM Escherichia coli WITH A POSSIBLE ROLE IN GENETIC RECOMBINATION
Author(s) -
Michio Oishi
Publication year - 1969
Publication title -
proceedings of the national academy of sciences of the united states of america
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.011
H-Index - 771
eISSN - 1091-6490
pISSN - 0027-8424
DOI - 10.1073/pnas.64.4.1292
Subject(s) - recbcd , recombination , escherichia coli , genetic recombination , enzyme , deoxyribonuclease , deoxyribonuclease i , deoxyribonucleases , mutant , mutation , biology , flp frt recombination , genetics , dna , microbiology and biotechnology , biochemistry , chemistry , base sequence , gene
A DNase which requires ATP for its function was purified fromE. coli and some of the characteristics of the purified enzyme were studied. This enzyme activity could not be detected in certain (recB andrecC ) recombination deficient mutant strains. The possible role of the enzyme in genetic recombination is discussed.