Open AccessA MUTATION WHICH CHANGES A MEMBRANE PROTEIN OF E. coli
Author(s) -
Masayori Inouye,
J. P. Guthrie
Publication year - 1969
Publication title -
proceedings of the national academy of sciences of the united states of america
Language(s) - English
Resource type - Journals
eISSN - 1091-6490
pISSN - 0027-8424
DOI - 10.1073/pnas.64.3.957
Subject(s) - mutation , dna replication , membrane protein , mutant , vesicle associated membrane protein 8 , dna , cell division , biology , gel electrophoresis , escherichia coli , membrane , cell , microbiology and biotechnology , biochemistry , gene
A temperature-sensitive mutant ofE. coli , which cannot synthesize DNA at high temperature but can continue cell division, shows a difference in a membrane protein fraction at high temperature by gel electrophoresis. This mutation of a bacterial membrane protein is unique. The protein may link DNA replication and cell division through the membrane.