A FACTOR PROMOTING THE INITIATION OF GLOBIN SYNTHESIS IN A RABBIT RETICULOCYTE CELL-FREE SYSTEM | Zendy

Joseph E. Fuhr | Zendy; Irving M. London | Zendy; Arthur I. Grayzel | Zendy

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A FACTOR PROMOTING THE INITIATION OF GLOBIN SYNTHESIS IN A RABBIT RETICULOCYTE CELL-FREE SYSTEM

Author(s) -

Joseph E. Fuhr,

Irving M. London,

Arthur I. Grayzel

Publication year - 1969

Publication title -

proceedings of the national academy of sciences

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.011

H-Index - 771

eISSN - 1091-6490

pISSN - 0027-8424

DOI - 10.1073/pnas.63.1.129

Subject(s) - reticulocyte , globin , incubation , protein biosynthesis , cell free system , biochemistry , biology , chemistry , microbiology and biotechnology , messenger rna , hemoglobin , in vitro , gene

The synthesis of globin has been studied in a reticulocyte cell-free system in which the initiation of polypeptide chain synthesis can proceed for as long as ten minutes of incubation. With this system, we have found evidence for a soluble factor in the reticulocyte that stimulates protein synthesis and appears to act by promoting initiation.

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