Open AccessTHE CYTOPLASMIC RNA OF HELA CELLS: NEW DISCRETE SPECIES ASSOCIATED WITH MITOCHONDRIA
Author(s) -
Cesare Vesco,
Sheldon Penman
Publication year - 1969
Publication title -
proceedings of the national academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.011
H-Index - 771
eISSN - 1091-6490
pISSN - 0027-8424
DOI - 10.1073/pnas.62.1.218
Subject(s) - cytoplasm , rna , polysome , hela , mitochondrion , biology , microbiology and biotechnology , biochemistry , chemistry , ribosome , cell , gene
Two new species of cytoplasmic RNA with approximate sedimentation values of 12S and 21S , and which appear associated with mitochondria, are described. The species are unmethylated, are relatively metabolically stable, and have a 43 per cent G + C content. Their synthesis is uniquely resistant to inhibition by UV irradiation. The 12S and 21S RNA do not appear to be components of polysome-like structures.
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