Template activity of uridylic acid-dihydrouridylic acid copolymers.
Author(s) -
Fritz Rottman,
P Cerutti
Publication year - 1966
Publication title -
proceedings of the national academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.011
H-Index - 771
eISSN - 1091-6490
pISSN - 0027-8424
DOI - 10.1073/pnas.55.4.960
Subject(s) - heterochrony , biology , progenitor cell , transcription factor , microbiology and biotechnology , progenitor , computational biology , genetics , stem cell , gene , ontogeny
It therefore appears that the expression of certain viral functions is dependent upon the physiological state of the cell at the time of infection. That the effect of a tumor virus on its host cell depends upon the operation of certain cellular functions has been previously shown by Temin'1 and Bader"2 for the RNA-containing Rous tumor virus. Summary.-A combined study by radioautography and immunofluorescence showed that the induction of cellular DNA synthesis in polyoma-infected cultures of mouse kidney cells occurs in productively infected cells.
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