CONTROL OF THE CIRCADIAN RHYTHM IN SEROTONIN CONTENT OF THE RAT PINEAL GLAND | Zendy

Solomon H. Snyder | Zendy; M H Zweig | Zendy; Julius Axelrod | Zendy; Josef E. Fischer | Zendy

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CONTROL OF THE CIRCADIAN RHYTHM IN SEROTONIN CONTENT OF THE RAT PINEAL GLAND

Author(s) -

Solomon H. Snyder,

M H Zweig,

Julius Axelrod,

Josef E. Fischer

Publication year - 1965

Publication title -

proceedings of the national academy of sciences

Language(s) - English

Resource type - Journals

eISSN - 1091-6490

pISSN - 0027-8424

DOI - 10.1073/pnas.53.2.301

Subject(s) - induced pluripotent stem cell , circadian rhythm , stem cell , serotonin , neuroscience , microbiology and biotechnology , biology , myocyte , electrophysiology , in vitro , computational biology , biochemistry , embryonic stem cell , receptor , gene

In this article, Axelrod and several members of his laboratory reported their findings on circadian rhythms and the results of a series of experiments on the pineal glands of rats. The researchers found that the circadian rhythm was synchronized by exposure to light, but otherwise operated independent of it. However, exposure to constant light, or blinding the rats altogether, significantly altered their circadian rhythms.

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