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all of the multiple enzyme types resulting from the treatment are more negatively charged than the original enzyme. With the exception of an enzyme that migrates slower than SS, the converted enzymes have migration rates identical to the autoand allodimer isozymes occurring in the homozygous and heterozygous combinations of the EF, E1N, and E18 alleles. It is postulated that these three alleles specify polypeptides with identical charges but differing in the number of conjugated positively charged side groups. Loss of varying numbers of these side groups after treatment with NaBH4 is proposed to explain the isozyme interconversions.

DISTRIBUTIVE PAIRING: THE SIZE-DEPENDENT MECHANISM FOR REGULAR SEGREGATION OF THE FOURTH CHROMOSOMES IN DROSOPHILA MELANOGASTER