Open AccessPLASMA AMINO ACID PATTERNS IN ALCOHOLISM: THE EFFECTS OF ETHANOL LOADING
Author(s) -
Frank L. Siegel,
Mary K. Roach,
Leon R. Pomeroy
Publication year - 1964
Publication title -
proceedings of the national academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.011
H-Index - 771
eISSN - 1091-6490
pISSN - 0027-8424
DOI - 10.1073/pnas.51.4.605
Subject(s) - induced pluripotent stem cell , in vitro , myocyte , stem cell , cell , cardiac electrophysiology , electrophysiology , cardiac muscle , microbiology and biotechnology , drug discovery , neuroscience , fluorescence microscope , fluorescence , chemistry , biophysics , biology , biochemistry , embryonic stem cell , anatomy , gene , physics , quantum mechanics
rather than to cause the absence of the wild-type enzyme. It is of interest that in both of these cases hybrid enzymes are formed in heterozygotes. Dimerization which has been proposed as the basis for hybrid vigor' may be a common feature of maize enzymes. Summary.-Two alleles of the E3 gene in maize specify electrophoretically separable esterases. As is the case with the pH 7.5 esterases formed by the E1 gene, a hybrid esterase with an intermediate migration rate is found in the E3 heterozygotes. The enzyme specified by one of the E3 alleles has a migration rate identical to that formed by one of the E1 alleles. * Research supported by National Science Foundation grant GB 302. 1 Schwartz, D., these PROCEEDINGS, 46, 1210 (1960).
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom