QUALITATIVE SURVEY OF RNA CODEWORDS
Author(s) -
Oliver W. Jones,
Marshall W. Nirenberg
Publication year - 1962
Publication title -
proceedings of the national academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.011
H-Index - 771
eISSN - 1091-6490
pISSN - 0027-8424
DOI - 10.1073/pnas.48.12.2115
Subject(s) - quality (philosophy) , business , water quality , environmental resource management , risk analysis (engineering) , environmental planning , geography , environmental science , ecology , biology , philosophy , epistemology
In this article, Jones and Nirenberg provide a progress report on code translation efforts. They find that almost every amino acid tested can be coded by a polymer containing only two bases. The article includes approximations of nineteen triplet codewords and suggests that any theory concerning the physical basis of the code must explain the available data revealing the high coding efficiency of polynucleotides, marked codeword specificity, and degenerate codewords. The degeneracy model of Gamov and Watson-Crick pairing are among some of the ideas discussed.
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