Open AccessThe Use of Sodium Nucleate in the Study of the Mutagenic Activity of Acriflavine in Escherichia Coli
Author(s) -
Evelyn M. Witkin
Publication year - 1950
Publication title -
proceedings of the national academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.011
H-Index - 771
eISSN - 1091-6490
pISSN - 0027-8424
DOI - 10.1073/pnas.36.12.724
Subject(s) - induced pluripotent stem cell , acriflavine , in vitro , fluorescence microscope , stem cell , myocyte , escherichia coli , fluorescence , microbiology and biotechnology , cell , chemistry , biophysics , biology , biochemistry , embryonic stem cell , quantum mechanics , physics , gene
In a previous study(1) neutral acriflavine was shown to induce mutations from phage-sensitivity to phage-resistance in Escherichia coli. The present report concerns an improved method of investigating the mutagenic potency of certain compounds, using acriflavine as a model.
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