Open AccessCryo-EM structures of wild-type and E138K/M184I mutant HIV-1 RT/DNA complexed with inhibitors doravirine and rilpivirine
Author(s) -
Abhimanyu Singh,
Brent De Wijngaert,
Marc Bijnens,
Kris Uyttersprot,
Hoai Viet Nguyen,
Sergio E. Martinez,
Dominique Schols,
Piet Herdewijn,
Christophe Pannecouque,
Eddy Arnold,
Kalyan Das
Publication year - 2022
Publication title -
proceedings of the national academy of sciences of the united states of america
Language(s) - English
Resource type - Journals
eISSN - 1091-6490
pISSN - 0027-8424
DOI - 10.1073/pnas.2203660119
Subject(s) - rilpivirine , dna , chemistry , reverse transcriptase , mutant , polymerase , nevirapine , crystallography , stereochemistry , human immunodeficiency virus (hiv) , rna , virology , biology , biochemistry , viral load , antiretroviral therapy , gene