Open AccessA genetic mammalian proportional–integral feedback control circuit for robust and precise gene regulation
Author(s) -
Timothy Frei,
Ching-Hsiang Chang,
Maurice Filo,
Asterios Arampatzis,
Mustafa Khammash
Publication year - 2022
Publication title -
proceedings of the national academy of sciences of the united states of america
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.011
H-Index - 771
eISSN - 1091-6490
pISSN - 0027-8424
DOI - 10.1073/pnas.2122132119
Subject(s) - synthetic biology , negative feedback , gene regulatory network , feedback control , regulator , transcription factor , biology , feedback loop , transcription (linguistics) , robustness (evolution) , computational biology , gene expression , gene , regulation of gene expression , control theory (sociology) , computer science , microbiology and biotechnology , genetics , control (management) , physics , engineering , artificial intelligence , control engineering , voltage , linguistics , computer security , philosophy , quantum mechanics