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Can the functional MRI responses to physical pain really tell us why social rejection “hurts”?
Author(s) -
Gian Domenico Iannetti,
André Mouraux
Publication year - 2011
Publication title -
proceedings of the national academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.011
H-Index - 771
eISSN - 1091-6490
pISSN - 0027-8424
DOI - 10.1073/pnas.1105451108
Subject(s) - skeletal muscle , insulin resistance , medicine , diabetes mellitus , pathological , bioinformatics , insulin , type 2 diabetes , obesity , neuroscience , endocrinology , biology
We read with great interest the recent PNAS report by Kross et al. (1). In this study, the authors selected a population of volunteers who recently experienced an unwanted breakup of their love relationship, and used functional MRI (fMRI) to record the brain responses elicited by (i) observing a photograph of their ex-partner as they think about being rejected and (ii) receiving actual nociceptive somatosensory simulation. Based on the observation of an “overlap between social rejection and physical pain[...] areas”, assumed to “support the sensory components of physical pain (secondary somatosensory cortex; dorsal posterior insula)”, …

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