The complete genomic sequence of Nocardia farcinica IFM 10152 | Zendy

Jun Ishikawa | Zendy; Atsushi Yamashita | Zendy; Yuzuru Mikami | Zendy; Yasutaka Hoshino | Zendy; Haruyo Kurita | Zendy; Kunimoto Hotta | Zendy; Tadayoshi Shiba | Zendy; Masahira Hattori | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

The complete genomic sequence of Nocardia farcinica IFM 10152

Author(s) -

Jun Ishikawa,

Atsushi Yamashita,

Yuzuru Mikami,

Yasutaka Hoshino,

Haruyo Kurita,

Kunimoto Hotta,

Tadayoshi Shiba,

Masahira Hattori

Publication year - 2004

Publication title -

proceedings of the national academy of sciences

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.011

H-Index - 771

eISSN - 1091-6490

pISSN - 0027-8424

DOI - 10.1073/pnas.0406410101

Subject(s) - biology , gene , genetics , plasmid , genome , chromosome , whole genome sequencing , virulence , nocardia , coding region , bacteria

We determined the genomic sequence of Nocardia farcinica IFM 10152, a clinical isolate, and revealed the molecular basis of its versatility. The genome consists of a single circular chromosome of 6,021,225 bp with an average G+C content of 70.8% and two plasmids of 184,027 (pNF1) and 87,093 (pNF2) bp with average G+C contents of 67.2% and 68.4%, respectively. The chromosome encoded 5,674 putative protein-coding sequences, including many candidate genes for virulence and multidrug resistance as well as secondary metabolism. Analyses of paralogous protein families suggest that gene duplications have resulted in a bacterium that can survive not only in soil environments but also in animal tissues, resulting in disease.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research