Enhancing sensitivity of lateral flow assay with application to SARS-CoV-2 | Zendy

Tao Peng | Zendy; Xiangpei Liu | Zendy; L. Garry Adams | Zendy; G. S. Agarwal | Zendy; Bruce Akey | Zendy; Jeffrey D. Cirillo | Zendy; Volker Deckert | Zendy; Sahar Delfan | Zendy; Edward S. Fry | Zendy; Zehua Han | Zendy; Philip Hemmer | Zendy; George W. Kattawar | Zendy; Moochan Kim | Zendy; MingChe Lee | Zendy; ChaoYang Lu | Zendy; Jon E. Mogford | Zendy; Reed Nessler | Zendy; Ben Neuman | Zendy; Xiaoyu Nie | Zendy; Jian-Wei Pan | Zendy; J. H. Pryor | Zendy; Navid Rajil | Zendy; Yanhua Shih | Zendy; Alexei V. Sokolov | Zendy; Anatoly A. Svidzinsky | Zendy; Dawei Wang | Zendy; Zhenhuan Yi | Zendy; А. М. Желтиков | Zendy; Marlan O. Scully | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Enhancing sensitivity of lateral flow assay with application to SARS-CoV-2

Author(s) -

Tao Peng,

Xiangpei Liu,

L. Garry Adams,

G. S. Agarwal,

Bruce Akey,

Jeffrey D. Cirillo,

Volker Deckert,

Sahar Delfan,

Edward S. Fry,

Zehua Han,

Philip Hemmer,

George W. Kattawar,

Moochan Kim,

MingChe Lee,

ChaoYang Lu,

Jon E. Mogford,

Reed Nessler,

Ben Neuman,

Xiaoyu Nie,

Jian-Wei Pan,

J. H. Pryor,

Navid Rajil,

Yanhua Shih,

Alexei V. Sokolov,

Anatoly A. Svidzinsky,

Dawei Wang,

Zhenhuan Yi,

А. М. Желтиков,

Marlan O. Scully

Publication year - 2020

Publication title -

applied physics letters

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.182

H-Index - 442

eISSN - 1077-3118

pISSN - 0003-6951

DOI - 10.1063/5.0021842

Subject(s) - sensitivity (control systems) , limiting , software portability , laser , covid-19 , materials science , optoelectronics , optics , nanotechnology , computer science , physics , electronic engineering , medicine , mechanical engineering , disease , pathology , infectious disease (medical specialty) , engineering , programming language

Lateral flow assay (LFA) has long been used as a biomarker detection technique. It has advantages such as low cost, rapid readout, portability, and ease of use. However, its qualitative readout process and lack of sensitivity are limiting factors. We report a photon-counting approach to accurately quantify LFAs while enhancing sensitivity. In particular, we demonstrate that the density of SARS-CoV-2 antibodies can be quantified and measured with an enhanced sensitivity using this simple laser optical analysis.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research