Invited Article: Label-free nerve imaging with a coherent anti-Stokes Raman scattering rigid endoscope using two optical fibers for laser delivery | Zendy

Keigo Hirose | Zendy; Shuichiro FUKUSHIMA | Zendy; T. Furukawa | Zendy; Hirohiko Niioka | Zendy; Mamoru Hashimoto | Zendy

Open Access

Invited Article: Label-free nerve imaging with a coherent anti-Stokes Raman scattering rigid endoscope using two optical fibers for laser delivery

Author(s) -

Keigo Hirose,

Shuichiro FUKUSHIMA,

T. Furukawa,

Hirohiko Niioka,

Mamoru Hashimoto

Publication year - 2018

Publication title -

apl photonics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.094

H-Index - 34

ISSN - 2378-0967

DOI - 10.1063/1.5031817

Subject(s) - endoscope , raman scattering , optics , materials science , laser , biomedical engineering , signal (programming language) , raman spectroscopy , physics , computer science , medicine , surgery , programming language

A coherent anti-Stokes Raman scattering (CARS) rigid endoscope using two optical fibers to deliver excitation beams individually is developed. The use of two optical fibers allows the correction of longitudinal chromatic aberration and enhances the CARS signal by a factor of 2.59. The endoscope is used to image rat sciatic nerves with an imaging time of 10 s. Imaging of the rabbit prostatic fascia without sample slicing is also demonstrated, which reveals the potential for the application of the CARS endoscope to robot-assisted surgery.A coherent anti-Stokes Raman scattering (CARS) rigid endoscope using two optical fibers to deliver excitation beams individually is developed. The use of two optical fibers allows the correction of longitudinal chromatic aberration and enhances the CARS signal by a factor of 2.59. The endoscope is used to image rat sciatic nerves with an imaging time of 10 s. Imaging of the rabbit prostatic fascia without sample slicing is also demonstrated, which reveals the potential for the application of the CARS endoscope to robot-assisted surgery.

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