Efficient extraction of oil from droplet microfluidic emulsions
Author(s) -
John Haliburton,
Samuel Kim,
Iain C. Clark,
Ralph A. Sperling,
David A. Weitz,
Adam R. Abate
Publication year - 2017
Publication title -
biomicrofluidics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.634
H-Index - 63
ISSN - 1932-1058
DOI - 10.1063/1.4984035
Subject(s) - microfluidics , aperiodic graph , merge (version control) , template , nanotechnology , materials science , extractor , extraction (chemistry) , computer science , chromatography , chemistry , process engineering , parallel computing , engineering , mathematics , combinatorics
Droplet microfluidic techniques can perform large numbers of single molecule and cell reactions but often require controlled, periodic flow to merge, split, and sort droplets. Here, we describe a simple method to convert aperiodic flows into periodic ones. Using an oil extraction module, we efficiently remove oil from emulsions to readjust the droplet volume fraction, velocity, and packing, producing periodic flows. The extractor acts as a universal adaptor to connect microfluidic modules that do not operate under identical flow conditions, such as droplet generators, incubators, and merger devices.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom